Abstract: Objective To investigate the effect of lumbar plexus and sciatic nerve block guided by nerve stimulator in elderly lower limb surgery. Methods A total of 76 elderly patients with lower limb surgery were selected from the Department of Anesthesiology of Yangdong District People’s Hospital, Yangjiang City from January 2019 to November 2021. They were divided into a routine group and an observation group （38 cases in each group） by random number table method; the routine group adopted continuous epidural anesthesia, and the observation group adopted a nerve stimulator-guided lumbar plexus and sciatic nerve block. The hemodynamics [systolic blood pressure （SBP）, diastolic blood pressure （DBP）, and heart rate （HR）] before anesthesia （T0）, 30 min after anesthesia （T1）, 60 min after anesthesia （T2）, and 1 h after surgery （T3）], anesthesia conditions, anesthesia effect, and adverse reactions were compared between two groups. Results There were no significant differences in SBP, DBP, and HR between the routine group and the observation group at T0, T1, T2, and T3 （P>0.05）; there were no significant differences in the onset time of sensory and motor block between the two groups （P>0.05）, and the observation group maintained longer sensation and movement than the routine group （P<0.05）; the observation group showed a better anesthesia effect and a lower incidence rate of adverse reactions than the routine group （P<0.05）. Conclusion Lumbar plexus and sciatic nerve block guided by nerve stimulator for elderly lower extremity surgery can stablize patient's hemodynamics, enhance the maintainance of sensory and motor block, and has a good anesthesia effect with high safety.

Key words: Lumbar plexus and sciatic nerve block, Nerve stimulator, Elderly patients, Lower limb surgery, Anesthetic effect