Abstract: Objective To investigate the effect of single-port laparoscopic-assisted total vaginal hysterectomy. Methods Sixty patients who underwent total hysterectomy in our hospital from January 2018 to April 2021 were selected and divided into an observation group （n=29） and a control group （n=31） according to the operation method. The observation group received single-port laparoscopic-assisted total vaginal hysterectomy, while the control group received traditional total vaginal hysterectomy. The operation conditions, Self-rating Anxiety Scale （SAS） score, Self-rating Depression Scale （SDS） score, Female Sexual Function Scale （FSFI） score, and Visual Analogue Scale （VAS） score were observed and recorded of the two groups, and the levels of serum estradiol （E₂）, follicular hormone （FSH）, and luteinizing hormone （LH） were examined before and after operation. Results The operation time and postoperative exhaust time in the observation group were （93.90±11.17） min and （29.50±3.12） min, respectively, which were significantly longer than those in the control group （P<0.05）. The VAS scores of the observation group immediately, 1 d, and 3 d after surgery were （4.10±0.97）, （2.50±0.83）, and （1.80±0.53） points, respectively, which were significantly lower than those of the control group （P<0.05）. The postoperative SAS and SDS scores of the observation group were （35.56±4.98） and （33.87±5.95） points, respectively, which were significantly lower than those of the control group （P<0.05）. The FSFI score of the observation group 3 months after operation was （26.19±5.01） points, which was significantly higher than that of the control group （P<0.05）. At 3 months after operation, the E₂ level in the observation group was （98.87±9.26） ng/L, which was significantly higher than that in the control group （P<0.05）, while the FSH and LH levels were （8.21±1.41） U/L and （11.31±2.03） U/L, respectively, which were significantly lower than those in the control group （P<0.05）. Conclusion Single-port laparoscopic-assisted total vaginal hysterectomy has a good effect, producing low negative emotion and little influence on sexual life and ovarian function of patients.

Key words: Single-port laparoscopic-assisted vaginal total hysterectomy, Negative emotion, Sexual life, Ovarian function