ISG15与乳腺癌

doi:10.3969/j.issn.2095-378X.2022.03.013

Abstract

Abstract: Breast cancer has become the most common women malignant tumor in the world. Nowadays, the diagnosis and treatment of breast cancer has gradually changed from traditional treatment methods to individualized and precise treatment methods. Interferon-stimulated gene 15 （ISG15） is related to the occurrence and development of many malignant tumors, and participates in tumor-related immune responses and the resistance of many chemotherapeutics. ISG15 can promote breast cancer cell movement, and participate in breast cancer-related tumor immunotherapy and various signaling pathways. These research findings provide new insights for breast cancer treatment. In this paper, the structure and function of ISG15, and its correlation with tumors, especially with breast cancer, were reviewed.

Key words: ISG15, Breast cancer, ISGylation, Chemo sensitivity, Tumor immunity

CLC Number:

R665.8

LI Wenqian, ZHANG Dongwei. ISG15 and breast cancer[J]. Surgical Research and New Technique, 2022, 11(3): 193-196.

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ISG15 and breast cancer

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