PVAT介导NO/NOS在脓毒血症患者血管舒缩活动中的作用研究进展

doi:10.3969/j.issn.2095-378X.2023.01.016

Abstract

Abstract: Sepsis is a serious and fatal disease, and many mechanisms are involved in its occurrence and development. Perivascular adipose tissue (PVAT), as an important participant in cardiovascular disease, is closely related to blood vessels, and can secrete a variety of active substances to participate in the changes of vasomotor activity. Nitric oxide (NO) and nitric oxide synthase (NOS) are important vasodilators. By reviewing previous literature, we explored the mechanism of PVAT-mediated NO/NOS regulation in vascular tone in sepsis, in the hope of contributing to the follow-up research and clinical practice.

Key words: Sepsis, Perivascular adipose tissue, Nitric oxide, Nitric oxide synthase, Vasotensin

CLC Number:

R365

LI Kun, QI Ran, LIU Nanbin. Research progress on role of PVAT-mediated NO/NOS in vasomotor activity in patients with sepsis[J]. Surgical Research and New Technique, 2023, 12(1): 60-65.

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Research progress on role of PVAT-mediated NO/NOS in vasomotor activity in patients with sepsis

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