Abstract: Objective To investigate the influence of ultrasound-guided intracavitary radiofrequency ablation combined with point stripping therapy on local blood circulation and coagulation function in patients with lower extremity varicose veins. Methods A total of 90 patients with varicose veins of lower limbs treated from October 2019 to November 2020 were divided into a control group and an observation group by random number table method, with 45 cases in each group. The control group was treated with traditional high ligation and stripping of great saphenous vein and point stripping of varicose vein, and the observation group was treated with ultrasound-guided intracavitary radiofrequency ablation combined with point stripping. The treatment results of the two groups were compared. Results There was no significant difference in venous blood flow velocity of both lower limbs between the two groups before operation （P> 0.05）. The venous blood flow velocity of both lower limbs in the observation group was faster than that in the control group 1 and 2 weeks after operation （P<0.05）. Before treatment, there were no significant differences in the levels of PT, FIB, and APTT between the two groups （P>0.05）. After treatment, there were significant differences in above indicators between the observation group and the control group （P<0.05）. Conclusion Ultrasound-guided intracavitary radiofrequency ablation combined with point stripping therapy has high application value in the treatment of varicose veins of lower limbs. It can improve the blood flow velocity and coagulation function of lower limbs and promote local blood circulation.

Key words: Ultrasound-guided intracavitary radiofrequency ablation, Point stripping therapy, Varicose veins of lower limbs, Blood circulation, Coagulation function