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Surgical Research and New Technique ›› 2024, Vol. 13 ›› Issue (3): 243-248.doi: 10.3969/j.issn.2095-378X.2024.03.015

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Research progress on application of exosomes in kidney transplantation

HUANG Yushi1, GUO Peixin1, MA Liyun1, HUI Jialiang2   

  1. 1. Department of Anesthesiology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong, China;
    2. Department of Organ Transplant, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong, China
  • Received:2024-05-13 Published:2024-10-17

Abstract: As one of the best treatments for end-stage renal disease, kidney transplantation has been widely carried out worldwide. However, due to the problems of immune rejection and postoperative complications in kidney transplantation, how to improve the success rate of kidney transplantation and prolong the life of transplanted kidney is still a major problem. Exosomes participate in the whole process of kidney transplantation, including preoperative diagnosis, postoperative immune rejection and other complications, because of their information transmission and material transport functions. This article expounded the important roles of exosomes in kidney transplantation from three aspects of immune rejection, immunosuppressant toxicity, and other post transplant complications, in order to provide new ideas for clinical diagnosis and treatment.

Key words: Kidney transplantation, Exosomes, Immune rejection

CLC Number: