生物活性陶瓷、骨形态发生蛋白、医用生物蛋白胶复合物诱导成骨活性研究

doi:10.3969/j.issn.2095-378X.2018.01.007

Abstract

Abstract: Objective To investigate the osteogenic activity induced by the complex of bioactive glass ceramics (BGC), bone morphogenetic protein (BMP), and biomedical fibrin glue (BFG).Methods Twenty SD rats were randomly divided into A, B, and C groups and each group as further divided into two subgroups. The complex of BGC, BMP, and BFG as used in subgroup 1, and ceramic artificial bone as used in subgroup 2. The transplantation effect was observed after 4 weeks.Results The implantation efficiency rate (70% vs. 60%), tissue growth efficiency rate (60% vs. 40%), and activity of alkaline phosphatase (0.441±0.082 vs.0.234±0.022) of the subgroup 1 were significantly higher than those of the subgroup 2 (P<0.05).Conclusion The complex of BGC, BMP, and BFG could ossify implants.

Key words: Bone morphogenetic protein, Ceramic artificial bone, Fibrous protein, Bone induction

CLC Number:

R459.9

SUN Buwei, LIU Baichuan. Osteogenic activity induced by complex of bioactive glass ceramics,bone morphogenetic protein, and biomedical fibrin glue[J]. Surgical Research and New Technique, 2018, 7(1): 24-27.

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Osteogenic activity induced by complex of bioactive glass ceramics,bone morphogenetic protein, and biomedical fibrin glue

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