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Surgical Research and New Technique ›› 2022, Vol. 11 ›› Issue (1): 1-8.doi: 10.3969/j.issn.2095-378X.2022.01.001

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Clinical prospects and opportunities for nanotechnology applied to imaging of osteoarthritis

LU Rong, CHEN Shuang   

  1. Department of Radiology, Huashan Hospital Affiliated to Fudan University, Shanghai 200040, China
  • Received:2022-01-10 Online:2022-03-28 Published:2022-08-17

Abstract: Osteoarthritis (OA) is the most common bone and joint disease. At present, it is considered no longer just a degenerative disease, but a systemic, metabolic, and inflammatory disease. OA is the main cause of disability of the elderly and one of the sources of social costs. Many new technologies and materials are under preclinical development to address this multifactorial disease. In terms of diagnosis, nano contrast agents for MRI, CT, and PA provide a lot of qualitative and quantitative information about cartilage structure and lesions, which are known biomarkers of OA. The opportunities for the development of nano medicine and the prospects of imaging and diagnosis based on nanotechnology are extremely broad.

Key words: Cartilage imaging, Advanced imaging, Nanotechnology

CLC Number: