Abstract: Objective To explore the effect of pain nursing intervention on improving the quality of life of patients with craniocerebral trauma in neurosurgery department. Methods From January 2018 to March 2020, 90 cases of patients with craniocerebral trauma were randomly divided into two groups, with 45 cases in each group. The control group received routine nursing, and the observation group received pain nursing on the basis of routine nursing. The scores of pain, comfort, bad mood, and life quality were compared between the two groups. Results At 12-48 h after operation, the pain score in the observation group was lower than that in the control group （P<0.05）, and the comfort score in the observation group was higher than that in the control group （P<0.05）. After nursing, the scores of anxiety and depression in the observation group were lower than those in the control group （P<0.05）, and the score of life quality in the observation group was higher than that in the control group （P<0.05）. Conclusion The application of pain nursing in patients with craniocerebral trauma in neurosurgery department can reduce postoperative pain, improve postoperative comfort, improve psychological status, and improve their quality of life.

Key words: Neurosurgery, Craniocerebral trauma, Pain care, Quality of life