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Original article

Experience of diagnosis and treatment for stone and carcinoma of intrahepatic bile duct

  • LIU Pengfei ,
  • LIU Kai ,
  • YE Chun ,
  • XU Wen
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  • 1.Department of Hepatobiliary Surgery,Tongji Hospital Affiliated to Tongji University, Shanghai 200065,China;
    2.Department of Radiology,Shanghai Ouyang Hospital,Shanghai 200081,China

Received date: 2017-01-03

  Online published: 2017-07-21

Abstract

Objective To discuss the diagnosis and treatment for stone and carcinoma of intrahepatic bile duct.Methods This article analyzed the effect of serum CA199,CEA,anemia degree,and intrahepatic bile duct stone course on diagnosis and the effect of different surgical Methods on prognosis of patients with stone and/or carcinoma of intrahepatic bile duct.Results In carcinoma + stone group,serum CA199 (71.43% vs.16.67%,P=0.001) and CEA (14.29% vs.0%,P=0.001) levels were higher than those of stone group; anemia degree was more serious (<10 g/L,66.67% vs.20.0%,P=0.001); the course of intrahepatic bile duct stone was longer (17.62 vs.11.30 years,P=0.001).The patients who received half liver resection with lymph node cleaning of hilus had a longer survival time compared with the patients who received local resection with lymph node cleaning of hilus (31.67 vs.17.4 months,P=0.042). Conclusion Observation of serum CA199,CEA,hemoglobin,and stone course in patients with intrahepatic bile duct stone may help diagnose whether intrahepatic bile duct carcinoma is combined.In addition,half liver resection with lymph node cleaning of hilus is recommended to patients with intrahepatic bile duct stone combined with intrahepatic bile duct carcinoma.

Cite this article

LIU Pengfei , LIU Kai , YE Chun , XU Wen . Experience of diagnosis and treatment for stone and carcinoma of intrahepatic bile duct[J]. Surgical Research and New Technique, 2017 , 6(2) : 91 -93 . DOI: 10.3969/j.issn.2095-378X.2017.02.006

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