Objective To analyze the changes and trends of serum Ca2+ concentration in patients with different degrees of brain injury.Methods The serum Ca2+concentrations of 79 patients with acute traumatic brain injury and 30 healthy blood donors were determined by atomic absorption spectrophotometry.Then 71 out of the 79 patients were selected to determine the serum Ca2+ concentration after hospital admission.Results The patients with acute traumatic brain injury showed significantly lower serum Ca2+ concentration than the healthy controls.The more serious the injury was,the steeper the decline was.Conclusion More severe brain injury is assoicated with lower GCS score and lower serum Ca2+concentration.
ZHONG Yongsheng
,
CAI Shirong
,
YANG Jinhua
,
CHEN Weiqiang
. Clinical study on blood calcium concentration changes after acute brain injury[J]. Surgical Research and New Technique, 2017
, 6(3)
: 182
-184
.
DOI: 10.3969/j.issn.2095-378X.2017.03.011
[1] 何百祥,张瑞娟,李奇,等.创伤性脑损伤后血清镁、钙离子检测的临床研究[J].中华现代外科学杂志,2008,5(8):571-573.
[2] 余飞,吴一芳,苏少华,等.颅内外血管吻合术治疗缺血性脑血管病的研究进展[J].外科研究与新技术,2013,2(1):45-48.
[3] Sakamoto T.Ionized magnesium in cerebrospinal fluid patients with head injuries[J].J Trauma,2005,58(6):1103-1109.
[4] 薛龙,尧荣凤,葛岭,等.轻型颅脑损伤后患者血清生物标志物GFAP-BPDs的相关性研究[J].外科研究与新技术,2014,3 (1):24-27.
[5] 王华.脑创伤患者脑脊液中钙、镁的变化及意义[J].创伤外科杂志,2002,4(5):289.
[6] 黄鹤飞,陈颖,蔡维艳,等.芍药苷对大鼠背根神经元细胞内Ca2+的影响[J].中国实验动物学报,2016,24(1):25-30.
[7] 张丽敏,郭雨童,曹磊,等.脑肿瘤患者围术期凝血-纤溶相关指标及血小板水平变化[J].检验医学与临床,2017,14(2):158-160.
[8] 刘时伟,贾光耀,梅炯.股骨头颈部血供的研究现状与展望[J].外科研究与新技术,2012,1(3):158-161.
[9] 张磊,陈汉明,张友华.右美托咪定在重型颅脑损伤术后患者治疗中的疗效分析[J].中国社区医师,2017,33(3):21-23.
[10] 周辉,余红,韩淑英.钙离子拮抗剂临床应用研究进展[J].华北煤炭医学院学报,2009,11(2):175-177.
[11] 包义君,陶山伟,李力卓,等.急性单发性创伤性颅脑损伤与离子紊乱的相关性研究[J].解放军医药杂志,2016,28(6):53-57.
