Objective To observe the effect of intraperitoneal perfusion during laparoscopic radical gastrectomy on advanced gastric cancer. Methods Eight two patients with advanced gastric cancer undergoing laparoscopic radical gastrectomy were randomly divided into a control group (n=41) and an observation group (n=41) by random number table method. The control group received laparoscopic radical gastrectomy only, and the observation group received laparoscopic radical gastrectomy and intraoperative intraperitoneal perfusion. The therapeutic effects were compared between the two groups. Results The postoperative drainage time, hospitalization time, and disease recurrence rate after 12 months of the observation group were shorter and lower than those of the control group (P<0.05); but no significant differences in operation time, intraoperative blood loss volume, postoperative exsufflation time, postoperative complication and side effect rates, and disease recurrence after 6 months were observed between the two groups. Conclusion Intraperitoneal perfusion during laparoscopic radical gastrectomy for advanced gastric cancer is safe and effective, can shorten hospitalization time and delay recurrence, and is worth promoting.
PAN Jianhai
,
LI Zhongmin
,
HUA Jiancan
. Observation of effect of intraperitoneal perfusion during laparoscopic radical gastrectomy on advanced gastric cancer[J]. Surgical Research and New Technique, 2020
, 9(1)
: 17
-19
.
DOI: 10.3969/j.issn.2095-378X.2020.01.005
[1] 张志平,胡礼,殷永芳,等.腹腔镜胃癌根治术联合腹腔热灌注化疗治疗82例进展期胃癌临床效果分析[J].肿瘤学杂志,2018,24(6):631-633.
[2] 牛松涛. 进展期胃癌姑息性切除术后腹腔热灌注联合静脉化学治疗临床疗效观察[J].新乡医学院学报,2017,34(6):474-477.
[3] 陈瑞云,张琳,刘文.胃癌术中腹腔热灌注化疗对术后胃肠道功能恢复的影响[J].中国现代普通外科进展,2017,20(6):458-459.
[4] 梁寒. 腹腔热灌注化疗技术临床应用专家共识(2016版)解读——胃癌腹膜转移的防治[J].临床外科杂志,2017,25(1):20-23.
[5] 陈新华,罗俊,刘浩,等.腹腔热灌注化疗预防局部进展期胃癌根治术后腹膜复发的研究进展[J].中华胃肠外科杂志,2018,21(5):593.
[6] 李洋,张明金,赵成功.小剂量洛铂术中腹腔灌注对胃肠肿瘤术后复发的影响[J].现代消化及介入诊疗,2018,23(4):33-35.
[7] 曾骞,周业江.术中腹腔注射洛铂联合术后化疗治疗进展期胃癌的安全性[J].广西医学,2018,40(16):1811-1814.
