《中国期刊全文数据库》收录期刊
《中国核心期刊(遴选)数据库》收录期刊
《中文科技期刊数据库》收录期刊
Review

ISG15 and breast cancer

  • LI Wenqian ,
  • ZHANG Dongwei
Expand
  • 1. Department of Breast Surgery, The Second Affiliated Hospital of Xiamen Medical College, Xiamen 361000, Fujian, China;
    2. Department of Breast Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150000, Heilongjiang, China

Received date: 2022-03-16

  Online published: 2022-12-29

Abstract

Breast cancer has become the most common women malignant tumor in the world. Nowadays, the diagnosis and treatment of breast cancer has gradually changed from traditional treatment methods to individualized and precise treatment methods. Interferon-stimulated gene 15 (ISG15) is related to the occurrence and development of many malignant tumors, and participates in tumor-related immune responses and the resistance of many chemotherapeutics. ISG15 can promote breast cancer cell movement, and participate in breast cancer-related tumor immunotherapy and various signaling pathways. These research findings provide new insights for breast cancer treatment. In this paper, the structure and function of ISG15, and its correlation with tumors, especially with breast cancer, were reviewed.

Cite this article

LI Wenqian , ZHANG Dongwei . ISG15 and breast cancer[J]. Surgical Research and New Technique, 2022 , 11(3) : 193 -196 . DOI: 10.3969/j.issn.2095-378X.2022.03.013

References

[1] Françoise V, Zhi W, Commere P, et al.USP18 and ISG15 coordinately impact on SKP2 and cell cycle progression[J]. Sci Rep, 2019, 9(1):4066.
[2] Dzimianski JV, Scholte F, Bergeron É, et al.ISG15: it's complicated[J]. J Mol Biol, 2019, 431(21):4203-4216.
[3] Juncker M, Kim C, Reed R, et al.ISG15 attenuates post-translational modifications of mitofusins and congression of damaged mitochondria in Ataxia Telangiectasia cells[J]. Mol Basis Dis, 2021,1867(6):166102.
[4] Xin BT, Jin G, Fernandez DJ, et al.Total chemical synthesis of murine ISG15 and an activity-based probe with physiological binding properties[J]. Org Biomol Chem, 2019, 17(48): 10148-10152.
[5] Jiang Y, Wang X.Structural insights into the species preference of the influenza B virus NS1 protein in ISG15 binding[J]. Protein Cell, 2019, 10(9): 681-687
[6] Freitas BT, Scholte F, Bergeron R, et al.How ISG15 combats viral infection[J]. Virus Res, 2020, 9(286): 198036.
[7] Burks J, Fleury A, Livingston S, et al.ISG15 pathway knockdown reverses pancreatic cancer cell transformation and decreases murine pancreatic tumor growth via downregulation of PDL-1 expression[J]. Cancer Immunol Immun,2019, 68(12): 2029-2039.
[8] Sandy Z, Costa I, Schmidt CK.More than meets the ISG15: Emerging roles in the DNA damage response and beyond[J]. Biomolecules, 2020, 10(11):1557.
[9] Swaim CD, Canadeo LA, Huibregtse JM .Approaches for investigating the extracellular signaling function of ISG15 - ScienceDirect[J]. Methods Enzymol, 2019, 618(1): 211-227.
[10] Liu H, Shi B, Zhang Z, et al.PRRSV vaccine strain-induced secretion of extracellular ISG15 stimulates porcine alveolar macrophage antiviral response against PRRSV[J]. Viruses, 2020, 12(9): 1009.
[11] Xin BT, Jin G, Fernandez DJ, et al.Total chemical synthesis of murine ISG15 and an activity-based probe with physiological binding properties[J]. Org Biomol Chem, 2019,17(48):10148-10152.
[12] Fernández DJ, Hess S, Knobeloch KP.Strategies to target ISG15 and USP18 toward therapeutic applications[J]. Front Chem, 2020, 21(7): 923.
[13] Pacella I, Spinelli F R, Severa M, et al.ISG15 protects human Tregs from interferon alpha nduced contraction in a cell‐intrinsic fashion[J]. Clin Transl Immunology, 2020, 9(12):1221.
[14] Held T, Basler M, Knobeloch K, et al.Evidence for an involvement of the ubiquitin‐like modifier ISG15 in MHC class I antigen presentation[J]. Eur J Immunol, 2021,51(1):138-150
[15] Lius S, Karaganiss S, Mo RF, et al.IFNβ treatment inhibits nerve injury-induced mechanical allodynia and MAPK signaling by activating ISG15 in mouse spinal cord.[J]. J Pain,2020;21(7-8):836-847.
[16] Buda G, Valdez RM, Biagioli G, et al.Inflammatory cutaneous lesions and pulmonary manifestations in a new patient with autosomal recessive ISG15 deficiency case report[J]. Allergy Asthma Clin Immunol,2020,16(1):77.
[17] Swaim CD, Canadeo LA, Monte KJ, et al.Modulation of extracellular ISG15 signaling by pathogens and viral effector proteins[J]. Cell Rep,2020,31(11):107772.
[18] Desai SD, Wood LM, Tsai YC, et al.ISG15 as a novel tumor biomarker for drug sensitivity[J]. Mol Cancer Ther, 2008,7(6):1430.
[19] Zhou S, Ren M, Xu H, et al.Inhibition of ISG15 enhances the anti-cancer effect of trametinib in colon cancer cells[J]. Onco Targets Ther,2019,26(12):10239-10250.
[20] Yi H, Zong Z, Wang Q, et al.ISG15 silencing increases cisplatin resistance via activating p53-mediated cell DNA repair[J]. Oncotarget,2017,8(64):107452-107461.
[21] Chen RH, Xiao ZW, Yan X Q, et al.Tumor cell-secreted ISG15 promotes tumor cell migration and immune suppression by inducing the macrophage M2-like phenotype[J]. Front Immunol, 2020,23(11):594775.
[22] Chen RH, Yong D, Ping H, et al.ISG15 predicts poor prognosis and promotes cancer stem cell phenotype in nasopharyngeal carcinoma[J]. Oncotarget, 2016,7(13):16910-16922.
[23] Kong EB, Kim HD, Kim J.Deleting key autophagy elongation proteins induces acquirement of tumor-associated phenotypes via ISG15[J]. Cell Death Differ, 2020,27(8):2517-2530.
[24] Alcalá S, Sancho P, Martinelli P, et al.ISG15 and ISGylation is required for pancreatic cancer stem cell mitophagy and metabolic plasticity[J]. Nat Commun,2020,11(1):2682.
[25] Sun J, Yan J, Qiao H Y, et al.Loss of TRIM29 suppresses cancer stem cell-like characteristics of PDACs via accelerating ISG15 degradation[J]. Oncogene.2020,39(3):546-559.
[26] Sainz B, Martin B, Tatari M, et al.ISG15 is a critical microenvironmental factor for pancreatic cancer stem cells[J]. Cancer Res, 2014,74(24):7309-20.
[27] Bektas N, Noetzel E, Veeck J, et al.The ubiquitin-like molecule interferon-stimulated gene 15 (ISG15) is a potential prognostic marker in human breast cancer[J]. Breast Cancer Res, 2008, 10(4): R58.
[28] Desai SD, Reed RE, Burks J, et al.ISG15 disrupts cytoskeletal architecture and promotes motility in human breast cancer cells[J]. Adv Exp Med Biol,2012,237(1):38-49.
[29] Tecalco-Cruz A, Cortes-Gonzalez CC, Cruz-Rams Z, et al.Interplay between interferon-stimulated gene 15/ISGylation and interferon gamma signaling in breast cancer cells[J]. Cell Signal, 2019,2(54):91-101.
[30] Forys J, Kuzmicki C, Saporita A, et al.ARF and p53 coordinate tumor suppression of an oncogenic IFN-β-STAT1-ISG15 signaling axis[J]. Cell Rep, 2014 ,7(2):514-526.
[31] Wood L M, Pan ZK, Seavey MM, et al.The ubiquitin-like protein, ISG15, is a novel tumor-associated antigen for cancer immunotherapy[J]. Cancer Immunol Immun, 2012,61(5):689-700.
[32] Burks J, Reed RE, Desai SD.Free ISG15 triggers an antitumor immune response against breast cancer: a new perspective[J]. Oncotarget, 2015,6(9):7221-7231.
Outlines

/