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外科研究与新技术（中英文）

外科研究与新技术（中英文） ›› 2026, Vol. 15 ›› Issue (3): 262-265.doi: 10.3969/j.issn.2095-378X.2026.03.014

• 论著 • 上一篇    下一篇

富血小板血浆联合TROPIS改良挂线法治疗复杂性肛瘘的临床疗效分析

陈升惠, 陈战   

  1. 陆军第七十三集团军医院普通外科,福建 厦门 361000
  • 收稿日期:2025-12-24 出版日期:2026-09-28 发布日期:2026-09-30
  • 作者简介:陈升惠（1994—）,女,硕士,住院医师,从事临床普通外科工作;电子信箱：chenyanxm77@163.com

Clinical efficacy analysis of platelet-rich plasma combined with TROPIS modified thread drawing method in treatment of complex anal fistula

CHEN Shenghui, CHEN Zhan   

  1. General Surgery Department of the 73rd Army Group Hospital, Xiamen 361000, Fujian, China
  • Received:2025-12-24 Online:2026-09-28 Published:2026-09-30

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摘要： 目的 探讨富血小板血浆（PRP）联合经肛括约肌间切开术（TROPIS）改良挂线法治疗复杂性肛瘘的临床价值。方法 选取2023年9月—2025年9月收治的90例复杂性肛瘘患者,按照随机数字表法分为对照组和研究组,每组各45例。对照组实施TROPIS-改良挂线;研究组在此基础上,联合PRP局部注射治疗,比较两组创面愈合指标（创面愈合时间,术后7、14 d创面渗出量）、肛门功能（术后1、3个月Wexner肛门失禁评分）及临床疗效（总有效率、复发率）。结果 相较于对照组,研究组创面愈合时间更短,术后7、14 d创面渗出量更少,术后1、3个月Wexner肛门失禁评分更低（肛门功能更佳）,治愈率提升、复发率下降（均P<0.05）。结论 PRP联合TROPIS-改良挂线可加速创面封闭、减少分泌物、维护肛门功能,并降低复发风险,具备推广前景。

关键词: 富血小板血浆, TROPIS改良挂线法, 复杂性肛瘘, 创面愈合, 肛门功能, 临床疗效

Abstract: Objective To explore the clinical value of platelet-rich plasma （PRP） combined with transanal opening of intersphincteric space （TROPIS） modified thread drawing method in the treatment of complex anal fistula. Methods A total of 90 cases of complex anal fistula admitted from September 2023 to September 2025 were included in the study. The patients were divided into two groups using a random number table method, with 45 cases in each group. The control group received TROPIS modified thread drawing, and the study group received PRP local injection therapy additionally. Wound healing indicators （wound healing time, wound exudation at postoperative 7 d and 14 d）, anal function （Wexner incontinence score at postoperative 1 month and 3 months）, and clinical efficacy （overall effectiveness and recurrence rate） were compared between the two groups. Results Compared with the control group, the study group had faster wound healing, less exudation at postoperative 7 d and 14 d, lower Wexner incontinence score at postoperative 1 month and 3 months （better anal function）, increased cure rate, and decreased recurrence rate （P<0.05）. Conclusion PRP combined with TROPIS modified thread drawing can accelerate wound closure, reduce secretions, maintain anal function, and reduce the risk of recurrence, with promising prospects for promotion.

Key words: Platelet-rich plasma, TROPIS modified thread drawing method, Complex anal fistula, Wound healing, Anal function, Clinical efficacy

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