《中国期刊全文数据库》收录期刊
《中国核心期刊(遴选)数据库》收录期刊
《中文科技期刊数据库》收录期刊

Surgical Research and New Technique ›› 2018, Vol. 7 ›› Issue (1): 54-57.doi: 10.3969/j.issn.2095-378X.2018.01.015

• Original article • Previous Articles     Next Articles

Effect of early fluid management on survival of patients with septic shock

ZHOU Juan1, WU Gang2, ZHANG Lei1   

  1. 1.Department of Surgical Intensive Care Unit, Tongji Hospital Affiliated to Tongji University, Shanghai 200065, China;
    2.Department of Urology, Tongji Hospital Affiliated to Tongji University, Shanghai 200065, China
  • Received:2018-01-22 Published:2019-12-12

Abstract: Objective To investigate the effects of different early fluid management approaches on the death risk of patients with septic shock.Methods Basic information, SOFA score, and daily intake and output volume of 119 patients with septic shock were collected. Correlation between liquid volume and outcome of patients with septic shock was analysed based on the liquid intake and output volume.Results The daily fluid balance in the first two days of the dead group was significantly higher than that of the survival group (P=0.031). The survival rate was significantly lower in the patients in the third quartile of 2-day cumulative fluid balance versus those in the first quartile (P=0.037). After 2 days of shock, the death risk in the high SOFA score group (>5 points) was higher than that in the low SOFA score group (<5 points) (P<0.001). The death risk was increased to 2.957 times in the patients in the third quartile of 2-day cumulative fluid balance (P=0.012).Conclusion The septic shock patients’ prognosis is related to the volume of early fluid input. The patients with a large volume of fluid intake showed poor prognosis. The SOFA score can reflect the severity of septic shock patients.

Key words: Septic shock, Fluid management, Mortality rate

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