非热远红外线照射联合藻酸盐银离子敷料促进肛瘘创面愈合的研究

doi:10.3969/j.issn.2095-378X.2026.01.014

Abstract

Abstract: Objective To investigate the clinical efficacy of non-thermal far-infrared irradiation combined with alginate silver ion dressing in promoting anal fistula wound healing. Methods A total of 90 patients with anal fistula who received treatment in the Department of Anorectal Surgery at our hospital from July 2023 to June 2024 were selected and randomly divided into an experimental group and two control groups （30 cases in each group）. The patients in the experimental group received treatment with non-thermal far-infrared irradiation combined with alginate silver ion dressing, those in the first control group received alginate silver ion dressing, and those in the second control group received non-thermal far-infrared irradiation. The local wound conditions （such as the degree of wound pain, bleeding and exudation, and healing condition）, overall efficacy, biomolecular indexes of wound exudate [vascular endothelial growth factor （VEGF）, matrix metalloproteinase 2 （MMP-2）, and tissue inhibitor of metalloproteinases-1 （TIMP-1）], and inflammatory factors [serum amyloid A （SAA）, interleukin 6 （IL-6）, and procalcitonin （PCT）] were compared between the three groups. Results On the 3rd, 5th, and 10th days after surgery, the visual analog scale （VAS） scores of the experimental group were significantly lower than those of the first and second control groups, the wound healing rate was significantly higher, and the wound healing period was significantly shorter （P<0.05）. The total effective rate of patients in the experimental group was significantly higher than those in the first and second control groups （P<0.05）. On the 7th day after surgery, the levels of VEGF and TIMP-1 in wound exudate in the experimental group were significantly higher than those in the first and second control groups, while the levels of MMP-2 were significantly lower （P<0.05）; the inflammatory factor levels of serum SAA, IL-6, and PCT in the experimental group were significantly lower than those in the first and second control groups （P<0.05）. Conclusion The clinical efficacy of non-thermal far-infrared irradiation combined with alginate silver ion dressing on wound healing in patients with anal fistula is significantly better than that of non-thermal far-infrared irradiation or alginate silver ion dressing alone, and it is worth clinical promotion.

Key words: anal fistula, wound healing, non-thermal far-infrared irradiation, alginate silver ion dressing

CLC Number:

R635

LIU Minghui, ZHANG Yan, DAI Linfeng, HUANG Lili, DING Rongxia, LIANG Congdie, ZHANG Feigong. Non-thermal far-infrared irradiation combined with alginate silver ion dressing to promote anal fistula wound healing[J]. Surgical Research and New Technique, 2026, 15(1): 59-64.

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Non-thermal far-infrared irradiation combined with alginate silver ion dressing to promote anal fistula wound healing

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