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Surgical Research and New Technique ›› 2013, Vol. 2 ›› Issue (4): 219-224.

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Hepatocellular carcinoma (HCC) & liver transplantation (LT)

ZHAO Ze-ming1, Becker Thomas2,3, FAN Yue-zu1, Ringe Bastian2, Klempnauer Jürgen2   

  1. 1.Department of General Surgery,Tongji Hospital,Tongji University School of Medicine, Shanghai 200065,China;
    2.Department of Abdominal and Transplantation Surgery,Medical School of Hannover,Carl-Neuberg Str1,Hanover 30625,Germany;
    3.Department of Abdominal and Transplantation Surgery,Arnold-Heller-Strae,Kiel 24105,Kiel University School of Medicine,Germany
  • Online:2013-12-28 Published:2013-04-25

Abstract: Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver.Liver transplantation for hepatocellular carcinoma (HCC) in patients with cirrhosis is a radical treatment of the tumor and associated precancerous state,especially for HCC developing within an established background of chronic liver disease.Shortage of organ donors has resulted in overall increase of waiting list time with increased risk of dropout due to tumor progression.Neoadjuvant therapies,transarterial chemoembolization (TACE),radiofrequency ablation (RFA) and percutaneous ethanol injection (PEI) have emerged as bridging therapy to control tumor growth.Although expansion of selection criteria is necessary,it should be assessed in the setting of prospective well-designed studies.This research presents German experience including single-center (medical school of Hannover) of undergoing transplantation for HCC.Rational use of liver transplantation is more beneficial for humanbeing.

Key words: Hepatocellular carcinoma, Liver transplantation, Living donor liver transplantation, Treatment

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