干细胞诱导分化为肝细胞调控机制研究进展

doi:10.3969/j.issn.2095-378X.2017.03.013

Abstract

Abstract: Stem cells have the potential for self-renewal and multi-directional differentiation.Experiments have proven that stem cells can differentiate into hepatocyte-like cells under certain conditions,with hepatocyte markers and functions.Liver transplantation is the only effective and curative way for end-stage liver disease,but is limited by a shortage of donor organs,high costs of surgery,long-term immune therapy,and so on.In light of that,stem cells are of potential application value in the treatment of end-stage liver disease.This review focused on the regulatory mechanisms of stem cells differentiated into hepatocyte-like cells.

Key words: Stem cells, Differentiation, Regulatory mechanism, Hepatocyte-like cells

CLC Number:

R329.2⁺1

XIAO Shuai, SHI Baomin. Progress on regulatory mechanism of stem cells differentiated into hepatocyte-like cells[J]. Surgical Research and New Technique, 2017, 6(3): 189-192.

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Progress on regulatory mechanism of stem cells differentiated into hepatocyte-like cells

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