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Surgical Research and New Technique ›› 2021, Vol. 10 ›› Issue (3): 209-213.doi: 10.3969/j.issn.2095-378X.2021.03.014

• Review • Previous Articles     Next Articles

Current application of percutaneous coronary intervention with drug-eluting stents

LIU Peng, YU Lingli   

  1. Department of Chemical Substance, Shanghai Center for Drug Evaluation and Inspection, Shanghai 201203, China
  • Received:2021-08-11 Online:2021-09-28 Published:2022-08-22

Abstract: Percutaneous coronary intervention combined with drug-eluting stents (DES) implantation has been recognized as the most effective and minimally invasive method for treating vascular diseases such as vascular stenosis caused by atherosclerosis. In order to resolve the problems existing in the clinical use of vascular stents, such as restenosis and in-stent thrombosis, various types of stents have been developed and approved to enter the market. DES integrate the dual advantages of traditional metal stents and antiproliferative drugs, and significantly reduce the incidence of in-stent restenosis and revascularization. This review summarized research progress on the drug loading, safety, and effectiveness of DES, aiming to improve the understanding of DES among clinicians, researchers, and patients and to better control related risks and make reasonable choices in clinical practice.

Key words: Drug-eluting stent, Coronary artery disease, In-stent restenosis, Restenosis, Biodegradable polymer

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