结肠癌患者循环肿瘤细胞与临床病理分期的相关性研究

doi:10.3969/j.issn.2095-378X.2018.01.001

Surgical Research and New Technique ›› 2018, Vol. 7 ›› Issue (1): 1-3.doi: 10.3969/j.issn.2095-378X.2018.01.001

• Original article • Next Articles

Relationship between circulating tumor cells and clinical pathologic stages in patients with colon cancer

GE Haiyan^1,2, ZHANG Zhenyu², FU Zhengwei², JI Fang², GAO Wei², GU Yueming¹, WANG Zhiqiang¹, MA Weiwei¹

1.Department of General Surgery, Pinghu Second People’s Hospital, Pinghu 314201, China;
2.Department of Gastrointestinal Surgery, East HospitalAffiliated to Tongji University, Shanghai 200120, China

Received:2017-12-18 Published:2019-12-12

Abstract

Abstract: Objective To understand the relationship between circulating tumor cells (CTCs) and clinical pathologic stages in patients with colon cancer.Methods CTCs counts in peripheral blood of untreated patients with colon cancer were detected by CellSearch technique.The relationship between CTCs and clinical pathologic stages of colon cancer was analyzed.Results CTCs in peripheral blood were detected in 40.6% (13/32) untreated cases of colon cancer.Significant relationships of positive CTCs were identified with colon cancer infiltration, TNM stage, and blood vessel infiltration (P<0.05), but not with age, sex, tumor size, and nerve infiltration.The Ⅲ+Ⅳ TNM stage patients had a much higher positive rate of CTCs than the Ⅰ+Ⅱ TNM stage patients (P<0.05).Conclusion CTCs can be detected in the peripheral blood of colon cancer patients, indicating higher clinicopathological stages.

Key words: Colon cancer, Circulating tumor cell, Tumor pathologic stage

CLC Number:

GE Haiyan, ZHANG Zhenyu, FU Zhengwei, JI Fang, GAO Wei, GU Yueming, WANG Zhiqiang, MA Weiwei. Relationship between circulating tumor cells and clinical pathologic stages in patients with colon cancer[J]. Surgical Research and New Technique, 2018, 7(1): 1-3.

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Relationship between circulating tumor cells and clinical pathologic stages in patients with colon cancer

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