结直肠癌患者血清miR-21检测的临床价值

doi:10.3969/j.issn.2095-378X.2019.01.001

Abstract

Abstract: Objective To investigate the clinical value of serum miR-21 levels in colorectal cancer patients before and after surgery.Methods Patients with confirmed colorectal cancer (colorectal cancer group, n=33) and healthy volunteers (control group, n=20) were enrolled in the study and detected for serum miR-21 expression levels before and after surgery by RT-PCR.Results The relative expression level of serum miR-21 in the colorectal cancer group before surgery was significantly higher than that in the control group (P<0.05); and the level of serum miR-21 after surgery was significantly lower than that before surgery (P<0.05).Conclusion Serum miR-21 is highly expressed in patients with colorectal cancer before surgery and lowly expressed after surgery, indicating a promising biomarker role for colorectal cancer, which is worthy of further evaluation.

Key words: Serum miR-21, Colorectal cancer, Prognosis

CLC Number:

R735.3

HE Xue, YIN Peihao. Clinical value of General serum miR-21 detection in patients with colorectal cancer[J]. Surgical Research and New Technique, 2019, 8(1): 1-3.

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Clinical value of General serum miR-21 detection in patients with colorectal cancer

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