Abstract: Objective To analyze the clinical efficacy and safety of maxillary sinus lift with oral implant on maxillary posterior tooth loss. Methods The clinical data of 98 patients with maxillary posterior tooth loss who received treatment from January 2018 to February 2021 were retrospectively analyzed. According to restoration methods, the patients were divided into a control group and a study group, with 49 cases in each group. The control group was fixed by conventional porcelain-fused-to-metal bridge, while the study group was fixed by maxillary sinus lift and implant. Clinical efficacy, retention function, masticatory function, aesthetic appearance, comfort, and incidence of complications （gingivitis, internal crown release, and bleeding） were compared between the two groups. Results The total effective rate of the study group was 100.00%, which was higher than that of the control group （91.84%）, and the difference was statistically significant （P<0.05）. The retention function, masticatory function, aesthetic appearance, and comfort scores of the study group were significantly higher than those of the control group, and the differences were statistically significant （P<0.05）. The incidence rate of complications in the study group （2.04%） was lower than that in the control group （12.24%）, and the difference was statistically significant （P<0.05）. Conclusion Maxillary sinus lift in the treatment of maxillary posterior tooth loss can improve the retention function, masticatory function, aesthetic appearance, and comfort, and reduce the incidence of complications.

Key words: Maxillary sinus lift, Maxillary posterior tooth loss, Clinical effect, Safety