Abstract: Objective To investigate the clinical effect of minimally invasive surgery of lumbar spine under endoscope through interlaminar approach. Methods A total of 180 patients with lumbar disc herniation admitted to the Department of Spinal Surgery of Meizhou People’s Hospital from May 2020 to May 2021 were selected as study subjects. According to the random number table method, they were divided into group A, group B, and group C. Group A （n=60） underwent traditional posterior lumbar open surgery. Group B （n=60） underwent transforaminal endoscopic minimally invasive lumbar surgery. Group C （n=60） underwent endoscopic minimally invasive lumbar surgery through interlaminar approach. The operation time and efficacy were compared among the three groups. Results The total effective rate of surgical treatment in group C was higher than that in group A and group B （P<0.05）. The total effective rate of surgical treatment in group B was higher than that in group A （P<0.05）. The operation time of group C was shorter than that of group A and group B （P<0.05）. The operation time of group B was shorter than that of group A （P<0.05）. Conclusion In the treatment of lumbar disc herniation by lumbar endoscopic minimally invasive surgery through interlaminar approach, the operation time is shorter and the clinical therapeutic effect is better than that by traditional lumbar posterior open surgery and lumbar endoscopic minimally invasive surgery through foraminal approach.

Key words: Interlaminar approach, Posterior lumbar open surgery, Transforaminal approach, Minimally invasive surgery of lumbar spine under spinal endoscope, Lumbar disc herniation