Abstract: Objective To investigate the effect of CT-guided abscess drainage in the treatment of pulmonary abscess on the levels of inflammatory factors in patients. Methods A total of 60 patients diagnosed with lung abscess were selected to participate in the study from January 2019 to January 2022. They were randomly divided into a control group （30 cases） and an observation group （30 cases）. The control group was given drug therapy and the observation group was given CT-guided abscess drainage, respectively. The disappearance time of symptoms, length of hospital stay, and the improvement of inflammatory factor levels were compared between the two groups. Results After treatment, the cough time [（11.16±1.45） d], disappearance time of high fever [（7.15±0.46） d], abscess absorption start time [（8.14±1.05） d], and length of hospital stay [（4.16±0.46） d] in the observation group were all shorter than those in the control group （P<0.05）. After treatment, the levels of various inflammatory factors in the two groups were lower than those before treatment, and the levels of procalcitonin [（81.15±4.16） ng/L], interleukin-6 [（11.15±1.76） ng/L], and C-reactive protein [（7.14±0.49） mg/L] in the observation group were lower than those in the control group （P<0.05）. Conclusion CT-guided abscess drainage in the treatment of lung abscess can significantly speed up the improvement of patients’ symptoms, shorten the length of hospital stay, and reduce the levels of inflammatory factors, which is worthy of popularization and application.

Key words: CT, Abscess drainage, Lung abscess, Inflammatory factor