肿瘤淋巴转移和淋巴管生成研究

Abstract

Abstract: With multiple growth factors of promoting lymphangiogenesis and lymphatic endothelial cell markers such as vascular endothelial growth factor-C/D,hyaluronic acid,prospero related homeobox gene-1,vascular endothelial growth factor receptor-3,podoplanin,1ymphatic vessel endothelial hyaluronan receptor-1 and D2-40 were found,more attention was paid to study on lymphatic metastasis and lymphangiogenesis in tumor.Currently,the study on lymphatic metastasis and lymphangiogenesis in tumor and its mechanism has become a new hot topic of cancer research.This paper is a brief review of recently discovered growth factors of promoting lymphangiogenesis and lymphatic endothelial cell markers,providing new ideas and targets for detection,diagnosis and treatment of malignant tumors.

Key words: Lymphatic metastasis, Lymphangiogenesis, Growth factors of promoting lymphangiogenesis, Lymphatic endothelial cell markers

CLC Number:

R730

LI Jie-jing, ZHUANG Zhi-gang, FAN Yue-zu. Research on lymphatic metastasis and lymphangiogenesis in tumor[J]. Surgical Research and New Technique, 2014, 3(1): 50-54.

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Research on lymphatic metastasis and lymphangiogenesis in tumor

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