上皮间质转化与肿瘤侵袭、转移

Abstract

Abstract: Tumor metastasis is an important stage in the development of tumor and the most principal lethal factors of malignant tumor patients.Transformation of epithelial mesenchymal (EMT),as the first step in the metastatic tumor,is a multiple genes,multi-steps and dynamic biology process closely associated with invasion and metastasis of malignant tumor^[1].The occurrence and development of EMT and their mechanism,research of a new effective way to control the invasion and metastasis of tumor or tumor treatment targets,is currently one of the hot topics in the study of tumor.This article summarizes the relationship between EMT,its relevant factors,signal transduction pathway and the invasion and metastasis of tumor.

Key words: Epithelial mesenchymal transformation, Tumor, Metastasis

CLC Number:

R730

ZHU Wei, FAN Yue-zu. Transformation of epithelial mesenchymal and invasion and metastasis of tumor[J]. Surgical Research and New Technique, 2014, 3(1): 55-59.

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Transformation of epithelial mesenchymal and invasion and metastasis of tumor

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