Abstract: Objective To investigate the effect of parenteral nutrition with fish oil on patients after gastrointestinal tumor surgery. Methods Sixty patients after gastrointestinal tumor surgery were randomly divided into an observation group (n=30, who received parenteral nutrition with fish oil) and a control group (n=30, who received conventional parenteral nutrition). The effects of the two groups were compared. Results After designed intervention, serum TP, ALB, PA, and TF in both groups were elevated, and the levels in the observation group were significantly higher than those in the control group (P<0.05); serum IL-6 and CRP and the incidence rate of complications in both groups were decreased, and the declines were steeper in the observation group than those in the control group (P<0.05). Conclusion Parenteral nutrition with fish oil not only provides better nutritional support for patients after gastrointestinal tumor surgery, but also reduces postoperative inflammatory reaction and complications, which is worthy of clinical promotion.

Key words: Gastrointestinal tumor, Surgery, Parenteral nutrition, Fish oil