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Surgical Research and New Technique ›› 2021, Vol. 10 ›› Issue (4): 291-294.doi: 10.3969/j.issn.2095-378X.2021.04.013

• Original article • Previous Articles     Next Articles

Effect assessment of preoperative vaginal misoprostol on cervical softening

WANG Mengling   

  1. Department of Gynecology, Heyuan Hospital of Traditional Chinese Medicine, Heyuan 517000, Guangdong, China
  • Received:2021-04-02 Online:2021-12-28 Published:2022-08-22

Abstract: Objective To analyze the effect of preoperative vaginal misoprostol on cervical softening. Methods A total of 58 patients undergoing induced abortion from January 2020 to January 2021 in our hospital were chosen as study subjects, and according to random number table, divided into a control group (29 cases, without preoperative cervical softening) and an observation group (29 cases, with preoperative cervical softening using vaginal misoprostol). Comparisons were performed in intraoperative bleeding volume, operation time, cervical dilation diameter, dilation time, uterine contraction degree, anesthetic drug dosage, cervical dilation degree, pain scores before and after surgery, and side effects such as abortion syndromes. Results The intraoperative bleeding volume and the anesthetic drug dosage in the observation group were lower than those in the control group; the operation time and the dilation time were shorter; the cervical dilation diameter was larger; the uterine contraction degree was higher (P<0.05). The effective cervical dilation rate in the observation group (100.00%) was higher than that in the control group (31.03%) (P<0.05). Before surgery, the pain score in the observation group was higher than that in the control group (P>0.05); whereas at postoperative 1 h, the pain score was lower (P<0.05). Both groups completed the surgery successfully. The observation group had one case of abortion syndrome (3.45%, 1/29), the control group had eight cases of abortion syndrome(27.59%, 8/29), and all the cases of abortion syndrome improved after treatment. No serious adverse side effects and complications occurred, such as incomplete abortion and uterine perforation. The cose of abortion syndromes in the observation group was lower than that in the control group (P<0.05). Conclusion Preoperative vaginal misoprostol application can reduce intraoperative bleeding volume, anesthetic drug dosage, pain degree after surgery, and abortion syndromes.

Key words: Vaginal administration, Misoprostol, Induced abortion, Cervical softening, Cervical dilation, Pain

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