Abstract: [Abstract] Objective:To explore the clinical effect of arthroscopic microfracture in the repair of full-thickness chondral defects of knee. Method:90 patients with full-thickness chondral defects of knee treated from May 2013 to April 2014 in our hospital were selected and randomly divided into control group and test group, 45 cases each group. The test group adopted the arthroscopic microfracture and control group adopted the articular debridement. The clinical effect of two groups was compared. After 6m of follow-up visits, HSS of knee function and Tegner score of athletic ability of two groups before and after treatment was compared. Result:The clinical effective rate of test group (91.1%) was higher than that of control group (71.1%) (P＜0.05); HSS of knee function and Tegner score of athletic ability of two groups after treatment was improved. However, HSS of knee function and Tegner score of athletic ability of test group was better than that of control group (P＜0.05).Conclusion: For patients with full-thickness chondral defects of knee, the arthroscopic microfracture has an obvious effect and can greatly improve the articular activity and function scores. It is worthy of clinical promotion.

Key words: Chondral Defects, Knee, Microfracture, Arthroscopic