抗淋巴管生成治疗结直肠癌研究进展

doi:10.3969/j.issn.2095-378X.2021.01.018

Abstract

Abstract: Tumor lymphangiogenesis is a complex process of tumor lymphatic endothelial cell proliferation, migration, and lymphangiogenesis. It is regulated by various signaling pathways, lymphangiogenic factors, and their receptors, which plays an important role in tumor lymphatic metastasis, and is related to the poor prognosis of patients. With the in-depth study of lymphangiogenesis and its endothelial markers, the molecular mechanism of lymphatic metastasis in colorectal cancer has been better understood, and new anti-tumor lymphangiogenesis treatments have been developed. The present paper reviewed studies of tumor lymphangiogenesis and its molecular regulation mechanisms, colorectal cancer lymphatic metastasis, and anti-lymphangiogenesis in colorectal cancer.

Key words: Colorectal cancer, Lymphangiogenesis, Lymphatic metastasis

CLC Number:

R735.3

WANG Hui, WANG Fangtao, FAN Yuezu. Research progress on anti-lymphangiogenesis in colorectal cancer[J]. Surgical Research and New Technique, 2021, 10(1): 64-67.

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Research progress on anti-lymphangiogenesis in colorectal cancer

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