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Surgical Research and New Technique ›› 2022, Vol. 11 ›› Issue (4): 270-273.doi: 10.3969/j.issn.2095-378X.2022.04.011

• Original article • Previous Articles     Next Articles

Synchronous occurrence of medullary thyroid carcinoma and papillary thyroid carcinoma: a case report and literature review

MA Qiang, LIANG Chunli   

  1. Department of Thyroid Surgery, East Hospital, Tongji University, Shanghai 200120, China
  • Received:2022-08-24 Online:2022-12-28 Published:2023-03-20

Abstract: Objective To investigate the clinicopathological features, diagnosis, and treatment of medullary thyroid carcinoma (MTC) complicated with papillary thyroid carcinoma (PTC). Methods A retrospective analysis was conducted of a case of MTC and PTC and related literature was reviewed. Results A female patient was admitted to the hospital due to bilateral thyroid nodules. Preoperative calcitonin: >2000.0 pg/mL, CEA: 132.0 ng/mL, pro-GPR: 440.0 ng/mL. Preoperative diagnosis: medullary carcinoma? Intraoperative frozen pathology suggested PTC on the left and MTC on the right. Total thyroidectomy with bilateral central lymph node dissection was performed. Postoperative pathological results revealed right MTC and left PTC. Conclusion Synchronous occurrence of MTC and PTC in a patient is rare. This case report and literature review provide references for the diagnosis and treatment of such patients.

Key words: Medullary thyroid carcinoma, Papillary thyroid carcinoma, Diagnosis, Treatment

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