Abstract: Objective To investigate the effect of 1∶1 infusion of fresh frozen plasma and leukocyte-removed suspended red blood cells on the indexes of thromboelastogram and prognosis of severe trauma emergency patients. Methods A total of 120 patients with severe trauma undergoing emergency blood transfusion were prospectively collected and divided into 1∶1 proportional infusion treatment group, 1∶2 proportional infusion treatment group, and 1∶3 proportional infusion treatment group according to different proportions of fresh frozen plasma infusion and leukocyte-removed suspended red blood cell infusion, 40 patients in each group. After infusion, comparisons were made among the three groups of thromboelastogram indexes [coagulation angle （α-Angle）, coagulation time （K） after blood transfusion, reaction time （R）, and maximum thrombus amplitude （MA）], as well as recording of the amount of bleeding 24 h after operation, the length of stay in intensive care unit （ICU）, the time to correct shock, and the time to recover blood volume. Results After infusion, the α-Angle and MA of the 1∶1 proportional infusion treatment group were higher than those of the 1∶2 and 1∶3 proportional infusion treatment groups, while the values of K and R were lower （P<0.05）. The ICU hospitalization time, shock correction time, and blood volume recovery time of the 1∶1 proportional infusion treatment group were shorter than those of the 1∶2 and 1∶3 proportional infusion treatment groups （P<0.05）. Conclusion Infusion of fresh frozen plasma and leukocyte-removed suspended red blood cells at a ratio of 1∶1 for emergency patients with severe trauma can effectively improve their coagulation state and provide positive assistance for their prognosis, and its application effect is worthy of affirmation.

Key words: Fresh frozen plasma, Leukocyte-removed suspended red blood cells, Severe trauma, Thromboelastogram index, Emergency