血管生成拟态与大肠癌肝转移相关性探究

Abstract

Abstract: Objective Explore the relationship between vasculogenic mimicry and liver metastasis of colorectal cancer. Methods Analysis of vasculogenic mimicry formation in 115 colorectal carcinoma patients by immunohistochemical staining. Among the colorectal carcinoma patients, 25 were with liver metastases and 90 without liver metastases. Monitor cancer recurrence and liver metastases of these 115 patients by surveying for 2 years. Restults Among patients with liver metastases, 64.0% were VM positive. While only 26.7% were VM positive among patients without liver metastases. Recurrence and liver metastases of patients without liver metastases before operation were statistically significant with VM existence with the P values of 0.0003 and less than 0.0001, respectively. Conclusion VM was positively associated with recurrence and liver metastases of colorectal cancer.

Key words: colorectal cancer, vasculogenic mimicry, liver metastasis

References

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Study of Correlation of vasculogenic mimicry and liver metastasis of colorectal cancer

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