Abstract: Objective To investigate the clinical effect of membrane anatomy guided precise surgical concept in laparoscopic radical gastrectomy for gastric cancer. Methods A total of 98 patients with advanced gastric cancer admitted to Guigang People's Hospital in Guangxi Zhuang Autonomous Region from January 2022 to January 2024 were selected as study subjects. They were randomly divided into a control group and an observation group, with 49 patients in each group. The control group received conventional laparoscopic radical gastrectomy treatment, while the observation group received laparoscopic radical gastrectomy treatment guided by membrane anatomy theory. The surgical time, intraoperative blood loss, number of lymph node dissection, first postoperative exhaust time, hospitalization time, postoperative pain score [by visual analogue scale （VAS）], and incidence of postoperative complications were compared between the two groups of patients. Results Compared with the control group, the surgery time of the observation group patients was longer, the intraoperative blood loss was lower, the number of lymph node dissections was higher, the first postoperative exhaust time and hospitalization time were shorter, the VAS score and incidence of complications were lower; the differences between the two groups were all statistically significant （P<0.05）. Conclusion The precise surgical concept guided by membrane anatomy has a remarkable effect on laparoscopic radical gastrectomy for gastric cancer, which can significantly reduce intraoperative bleeding, postoperative pain, and incidence of complications, and promote postoperative recovery of patients. It is worth applying and promoting.

Key words: Precision surgical concept under the guidance of membrane anatomy, Gastric cancer, Laparoscopic radical gastrectomy for gastric cancer, Clinical effectiveness