Abstract: Objective To analyze the clinical value of laparoscopic radical gastrectomy combined with hyperthermic infusion chemotherapy for advanced gastric cancer.Methods Eighty patients with advanced gastric cancer were selected from October 2017 to October 2018 in our hospital and divided into experimental group and control group with 40 cases in each group.The control group was treated with laparoscopic radical gastrectomy.The patients in the experimental group were treated with laparoscopic radical gastrectomy combined with hyperthermic infusion chemotherapy.The recovery time of gastrointestinal function,clinical treatment effect,postoperative hospitalization time,and incidence of complications were compared between the two groups.Results The total incidence rate of complications in the experimental group (5%) was less than that in the control group (P<0.05),so were the hospitalization time (P<0.05) and the recovery time of gastrointestinal function.The total effective rate of the experimental group (97.5%) was higher than that of the control group (75%,P<0.05).Conclusion For patients with advanced gastric cancer,laparoscopic radical gastrectomy combined with hyperthermic chemotherapy is effective by improving gastrointestinal function,shortening postoperative hospital stay,and lowering clinical complications.

Key words: Advanced gastric cancer, Laparoscopy, Hyperthermic perfusion, combined therapy, Radical operation, Therapeutic effect