Table of Content

28 June 2018, Volume 7 Issue 2 Previous Issue    Next Issue

Original article

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Dual-regulated oncolytic adenoviruses carrying TAp63 geneinhibit the growth of colon cancer stem cells LUO Qifeng, DU Min, DAI Zhenling, FU Zhengwei, ZHANG Zhenyu, Shiva BASNET, GE Haiyan 2018, 7 (2):  77-82.  doi: 10.3969/j.issn.2095-378X.2018.02.001 Abstract ( 153 )   PDF (2028KB) ( 603 )   Save Objective To construct dual-regulated oncolytic adenoviruses carrying TAp63 gene and detect their antitumor effect on colon cancer stem cells.Methods Colon cancer stem cells were screened by flow cytometry.New recombinant adenoviruses were constructed according to the Adeasy system.The viral DNA acted as a template for PCR, then agarose gel electrophoresis assay was applied to confirm the viral DNA.CCK8 assay and cell apoptosis assay were used to detect the effects of recombinant adenoviruses on the proliferation of colon cancer stem cells and human normal liver cells, as well as on the apoptosis of colon cancer stem cells.Results The proportion of CD133/CD44 double positive cells was (42.47±0.81)% in HCT116 cells (P<0.05).The recombinant adenoviruses Arsz-TAp63 were successfully constructed without wild-type adenovirus contamination, and were shown to inhibit the proliferation of colon cancer stem cells HCT116 CD133/CD44, but not human normal liver cells L-02, and promote the apoptosis of HCT116 CD133/CD44 cells.Conclusion The recombinant adenoviruses Arsz-TAp63 selectively inhibit the proliferation and induce the apoptosis of HCT116 CD133/CD44 cells. References | Related Articles | Metrics

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Finite element study and clinical efficacy analysis on Pauwels type Ⅲ femoral neck fractures fixed with four screws RAO Zhitao, ZHANG Yingqi, CHEN Lei, WANG Jiaqi, WANG Shuqing 2018, 7 (2):  83-88.  doi: 10.3969/j.issn.2095-378X.2018.02.002 Abstract ( 184 )   PDF (4124KB) ( 440 )   Save Objective To investigate the biomechanical properties and clinical outcomes of four-screw configuration used for internal fixation of Pauwels type Ⅲ femoral neck fractures.Methods A three-dimensional finite element model (FEM) of Pauwels type Ⅲ femoral neck fracture was established and analyzed in three fixation groups (Group 1, an inverted triad of screws; Group 2, four-screw configuration with one transverse screw and three parallel inverted triangle screws; Group 3, hybrid fixation of one dynamic hip screw and one de-rotation screw).Simulated load with one leg standing was applied and then the stress and displacement of the model were calculated to compare the biomechanical stability of different fixation strategies.Retrospective clinical analysis of 31 cases with Pauwels type Ⅲ femoral neck fractures using four-screw fixation was conducted.Results Biomechanically, finite element analysis showed that the strongest construct for stabilizing a Pauwels type Ⅲ femoral neck fracture was Group 3, followed in descending order by Group 2 and Group 1, and the screw displacement in descending order was Group 3, Group 2, and Group 1.Clinically, 31 patients with Pauwels type Ⅲ femoral neck fractures were treated with four-screw configuration; 24 patients (77.4%) were followed up for 24 months and over (24-62 months).None of the cases was nonunion and the mean union time was 16.3 weeks (12-24 weeks).Three cases (12.5%) had necrosis of femoral head.The mean Harris score of hip function was 80±8.5 points, and the excellent-and-good rate was 83.3%.Conclusion The four-screw configuration with one transverse screw and three parallel inverted triangle screws can be used to fix Pauwels type Ⅲ femoral neck fracture.Further studies with larger sample size and longer follow-up are required to assess its clinical efficacy. References | Related Articles | Metrics

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Obesity-induced male infertility reversed by sleeve gastrectomy in a rat model LI Jiajing, WANG Yanqiu, BIAN Cuidong, WAN Xiaodong, XIANG Jun 2018, 7 (2):  89-92.  doi: 10.3969/j.issn.2095-378X.2018.02.003 Abstract ( 139 )   PDF (2581KB) ( 374 )   Save Objective Obesity is a metabolic disease and induces a variety of diseases including infertility.Sleeve gastrectomy shows encouraging Results in terms of weight loss and quality of life improvement.This study aims to determine whether sleeve gastrectomy could reverse obesity-induced fertility impairment in male SD rats.Methods After 16 weeks of a chow diet (CD) or a high-fat diet (HFD) challenge, the HFD rats were given sleeve gastrectomy or sham operation and then fed with HFD for another 8 weeks.Serum sex hormone and sperm quality in the three groups were compared.Results Sleeve gastrectomy not only decreased HFD-induced obesity, but also reversed HFD-induced increase in teratozoospermia and decreases in sperm motility and progressive motility.The expression of sex hormones increased after sleeve gastrectomy.Conclusion Sleeve gastrectomy could reverse obesity-induced fertility impairment in rats. References | Related Articles | Metrics

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Significance of P504s, P63, PSMA, and Ck34βE12 in identification of benign and malignant prostate lesions LI Guocheng 2018, 7 (2):  93-96.  doi: 10.3969/j.issn.2095-378X.2018.02.004 Abstract ( 300 )   PDF (768KB) ( 366 )   Save Objective To explore the significance of P504s, P63, PSMA, and Ck34βE12 in the identification of benign and malignant prostate lesions.Methods A total of 112 surgical resection specimens of transrectal ultrasound guided prostate biopsy were collected from the Traditional Chinese Medicine Hospital of Heze City of Shandong Province from January 2014 to December 2016.All specimens were prepared for paraffin section and detected for P504s, P63, PSMA, and Ck34βE12.According to the proportion of positive cells, the detection Results were classified as follows.The accuracy, sensitivity, and specificity of P504S, P63, PSMA, and Ck34βE12 detected separately and jointly in the diagnosis of prostate cancer were compared.Results The positive rate of P504s in prostate cancer patients was 100.00%, and the dispersion positive rate was up to 62.75%, significantly higher than those in the AAH, BCH, and BPH patients.The positive rates of P63 and Ck34βE12 in prostate cancer patients were both 0%, while those in the HGPIN, AAH, BCH, and BPH patients were all 100.00%.The positive rates of PSMA in prostate cancer and HGPIN patients were 98.04% and 90.91%, respectively, while those in the AAH, BCH, and BPH patients were 13.33%, 11.11%, and 9.52%, respectively.The accuracy, sensitivity, and specificity of combined detection of P504s, P63, PSMA, and Ck34 reached 100.00%, 97.85%,and 98.24%, respectively, showing clinical diagnostic value.Conclusion For the diagnosis of prostate cancer, combined detection of P504s, P63, PSMA, and Ck34βE12 could significantly increase the accuracy, sensitivity, and specificity. References | Related Articles | Metrics

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Clinical observation of laparoscopic adhesiolysis on intestinal adhesion after appendectomy in children ZHOU Fan, ZHANG Yunsheng, TANG Shiju 2018, 7 (2):  97-100.  doi: 10.3969/j.issn.2095-378X.2018.02.005 Abstract ( 193 )   PDF (825KB) ( 503 )   Save Objective To observe the clinical effect of laparoscopic adhesiolysis for intestinal adhesion in children after appendectomy.Methods A total of 60 children with intestinal adhesion who underwent appendectomy in Kanghua Hospital from June 2015 to June 2017 were selected and divided into a control group and an observation group by random number table method, with 30 cases in each group.The control group underwent open laparoscopic adhesion dissection, while the observation group received laparoscopic adhesiolysis.The perioperative effect indices, postoperative complications, and quality of life scores of the two groups were observed.Results The operation time, intraoperative blood loss, gastrointestinal function recovery time, abdominal pain disappearing time, and hospital stay of the observation group were significantly lower than those of the control group (P<0.05); the complication rate of the observation group was also significantly lower than that of the control group (5.00 %vs. 20.00%, P<0.05).The scores of physical, emotional, social/family, and functional well-being at 6 months post operation of the observation group were significantly higher than those of the control group (P<0.05).Conclusion Laparoscopic adhesiolysis has an excellent clinical effect on intestinal adhesions in children after appendectomy, with little trauma, quick recovery, and less postoperative complications, which improves quality of life and is worth promoting. References | Related Articles | Metrics

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Sedative and postoperative cognitive effects of intraspinal administration of dexmedetomidine at different doses on elderly patients with lower extremity surgery MAO Shanshan, HUANG Qun 2018, 7 (2):  101-104.  doi: 10.3969/j.issn.2095-378X.2018.02.006 Abstract ( 175 )   PDF (776KB) ( 520 )   Save Objective To compare the effects of intraspinal administration of different dosages of dexmedetomidine (DEX) on sedation, shivering, and early postoperative cognitive function of elderly patients.Methods Elderly patients with lower extremity surgery under intravertebral anesthesia were randomly divided into group L, group M, and group H, with 25 cases in each group.The patients were given intraspinal anesthesia, and 10 min later slowly injected with DEX 0.5μg/kg.Then, the group L, group M, and group H were injected with DEX at 0.2 μg/(kg·h), 0.4 μg/(kg·h), and 0.7 μg/(kg·h) for maintenance.All the three groups stopped injection 30 min before the end of the surgery.Ramsay score, BIS, MAP, and HR, shivering grade, and shivering rate of the three groups were compared before anesthesia (T0), at the time of injection (T1), and 10 min (T2), 20 min (T3), 30 min (T4), and 1 h (T5) after surgery.Simple Mental State Scale (MMSE) was used at 1d and 7d after the surgery to measure the preoperative and postoperative incidence rate of cognitive dysfunction.Results The Ramsay scores of the three groups at T2, T3, and T4 were significantly higher than those at T0 and T1 (P<0.05), and at the same time point, the Ramsay scores of the group M and group H were higher than those of the group L (P<0.05).The BIS values of the three groups at T2, T3, and T4 were significantly lower than those at T0 and T1 (P<0.05), and at the same time point, the BIS values of the group M and group H were lower than those of the group L (P<0.05).The MAP and HR of the three groups at T2, T3, and T4 were significantly lower than those at T0 and T1 (P<0.05), and at the same time point, the MAP and HR of the group M and group H were lower than those of the group L (P<0.05).The incidence rates of shivering of the group M and group H were significantly lower than that of the group L (P<0.05).At 7 d after the operation, the MMSE scores of the three groups were significantly lower compared with preoperation, but there was no statistically significant difference in the incidence rate of POCD.Conclusion Compare with preoperation, DEX shows a better sedative effect and prevents POCD and shivering in elderly patients with lower extremity surgery.DEX at 0.4 μg/(kg·h) is appropriate in clinical application. References | Related Articles | Metrics

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Clinical observation of celecoxib preemptive analgesia for painless abortion MA Yanfeng, XU Jiliang, PENG Sheng 2018, 7 (2):  105-107.  doi: 10.3969/j.issn.2095-378X.2018.02.007 Abstract ( 204 )   PDF (761KB) ( 466 )   Save Objective To observe the clinical effect of celecoxib preemptive analgesia for painless abortion.Methods Eighty pregnant women in early pregnancy were randomly divided into celecoxib group (treatment group) and control group, 40 cases in each group.Treatment Group received oral celecoxib 400 mg at 2 h before operation for preemptive analgesia, while control group did not.Both groups were given intravenous fentanyl 0.05 mg + propofol 2.0 mg/kg, followed by propofol as needed.BP, HR, SPO2, and RR were recorded before anesthesia (T0), at disappearance of consciousness (T1), at cervix expansion (T2), at opening eyes by prompting (T3), and at 1h after operation (T4); induction time, recovery time, intraoperative total propofol dosage, intraoperative limb movement, glossoptosis, respiratory depression, intraoperative blood loss, and postoperative pain and other adverse reactions were recorded; VRS pain scores at 15, 30, and 60 min after surgery were recorded.Results There were no significant differences in BP, HR, SPO2, and RR at the 5 time points (P>0.05).Treatment Group patients’ anesthesia recovery time was significantly shorter than that of control group patients’, and the total propofol dosage was less (P<0.05).There was no significant difference in intraoperative blood loss between the two groups (P>0.05).In treatment group, the incidence rates of glossoptosis and respiratory depression were significantly lower than those in control group (P<0.05).The pain scores of VRS in treatment group were significantly lower than those in control group at different time points after waking up (P<0.05).Conclusion Celecoxib preemptive analgesia for painless abortion can reduce intraoperative propofol dosage and postoperative pain, while not increase blood loss and the incidence of respiratory depression or other adverse reactions. References | Related Articles | Metrics

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Diagnostic difference of pancreatic lesion by CT scan and CT enhancement HUAN Weizhou 2018, 7 (2):  108-110.  doi: 10.3969/j.issn.2095-378X.2018.02.008 Abstract ( 445 )   PDF (750KB) ( 832 )   Save Objective To discuss diagnostic difference of pancreatic lesion by using CT scan and CT enhancement.Methods A toal of 63 patients from Shuyang Hospital Affiliated to Nanjing University of Traditional Chinese Medicine (Shuyang Hospital of Traditional Chinese Medicine) underwent CT scan and CT enhancement of abdomen.The images of blood supply, density, boundary, invasion of surrounding blood vessels, vascular cancer embolus, and surrounding lymph nodes as well as the detection rate of pancreatic lesion were analyzed.Results Among the 63 cases, there were 43 cases of pancreatic cancer, 10 cases of pancreatic cyst, 5 cases of pancreatic endocrine tumor, and 5 cases of serous cystadenoma.The detection rate of pancreatic lesion by CT scan(85.71% [30/35]) was significantly lower than that by CT enhancement(100% [28/28]).In addition, CT enhancement provided images of blood supply, invasion of surrounding blood vessels, vascular cancer embolus, and images and intensity surrounding lymph nodes.Conclusion CT enhancement can provide more diagnostic information for operation than CT scan. References | Related Articles | Metrics

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Observation of wound pain relief and healing effects of different methods post hemorrhoids operation ZHENG Xiaomin, CHEN Huafang, SUN Peiqin 2018, 7 (2):  111-114.  doi: 10.3969/j.issn.2095-378X.2018.02.009 Abstract ( 286 )   PDF (763KB) ( 368 )   Save Objective To compare the effects of different Methods on wound pain relief and healing after hemorrhoids operation.Methods A total of 440 severe mixed hemorrhoids patients from January 2015 to December 2017 were selected and given external dissection and internal ligation operation of mixed hemorrhoids.After operation, the cases were divided into three groups according to the wound treatment method they received: hemorrhoids sitz bath plus alginate dressing, hemorrhoids sitz bath plus povidone iodine gauze, and potassium permanganate sitz bath plus povidone iodine gauze.At 1, 3, and 5 days after sitz bath, the pain degree was evaluated by VAS; errhysis, edema, and granulation after 5 days were compared among the two groups.Results At 1, 3, and 5 days after operation, the VAS score of the patients in the hemorrhoids sitz bath plus alginate dressing group was significantly lower than the scores of the other two groups (P<0.05).At 5 days after operation, the development of errhysis, edema, and granulation of the patients in the hemorrhoids sitz bath plus alginate dressing group was superior to the other two groups (P<0.05).Conclusion Hemorrhoids sitz bath plus alginate dressing shows better healing effects on errhysis, edema, and granulation with shorter healing time post hemorrhoids operation than hemorrhoids sitz bath plus povidone iodine gauze and potassium permanganate sitz bath plus povidone iodine gauze. References | Related Articles | Metrics

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Clinical effects of modified longitudinal incision and transversesuture on chronic anal fissure ZHU Haitao 2018, 7 (2):  115-117.  doi: 10.3969/j.issn.2095-378X.2018.02.010 Abstract ( 152 )   PDF (754KB) ( 260 )   Save Objective To explore the clinical effect of improved longitudinal incision and transverse operation on chronic anal fissure.Methods Sixty patients with chronic anal fissure who were admitted to Fengshun County People’s Hospital from September 2015 to October 2017 were enrolled in the study and divided into an experimental group and a reference group according to the time of admission.The reference group received conventional longitudinal incision and transverse suture, while the experimental group received modified operation.The effect of surgical treatment was compared between the two groups of patients.Results The experimental group showed shorter wound healing time than the reference group (P<0.05).The reference group had less pain and mild-to-moderate edema patients, more severe pain and edema patients (P<0.05), and more wound infection patients than the experimental group (P<0.05).The complication rate in the reference group was 6.67%, and the recurrence rate was 10.00%.There was no recurrence or complication in the experimental group, and the recovery of anus was good.The recurrence rate and the incidence rate of complications between the two groups were significantly different (P<0.05).The quality of life scale scores of the experimental group were higher than those of the reference group (P<0.05).Conclusion Modified longitudinal incision and transverse suture has significant effects on chronic anal fissure, showing good postoperative conditions, no complications, and improved quality of life of the patients, which is worthy of clinical application. References | Related Articles | Metrics

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Clinical analysis of physical therapy combined with exercise rehabilitation in the treatment of acute rotator cuff injury XU Chaojun, YE Zikun 2018, 7 (2):  118-121.  doi: 10.3969/j.issn.2095-378X.2018.02.011 Abstract ( 150 )   PDF (765KB) ( 538 )   Save Objective To evaluate the clinical effects of physical therapy combined with exercise rehabilitation on acute rotator cuff injury.Methods Eighty patients with acute rotator cuff injury were divided into observation group and control group according to treatment methods.The patients in the observation group were treated with physical therapy combined with exercise rehabilitation training, while the patients in the control group were treated only with physical therapy.After the treatment, the clinical effects of the two groups were compared.Results The total effective rate of the observation group was 92.5%, which was significantly higher than that of the control group (45.0%).Before the treatment, the specific scores of the University of California at Los Angeles (UCLA) shoulder scale were similar in the two groups.After the treatment, the scores of pain, function, active forward flexion, strength of forward flexion, and satisfaction of the observation group were significantly higher than those of the control group, and the VAS scores of the observation group were significantly lower than those of the control group.The active forward range of motion (ROM) and external rotation ROM of the observation group were significantly higher than those of the control group (P < 0.05).Conclusion The treatment of acute rotator cuff injury by physical therapy combined with exercise rehabilitation shows a high total effective rate and definite clinical effects including excellent recovery of shoulder joint ROM and reduced pain, which is beneficial to recovery from acute rotator cuff injury. References | Related Articles | Metrics

Review

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Mechanism and clinical value of long non-coding RNA in pancreatic cancer ZHANG Rundong, AI Kaixing 2018, 7 (2):  122-126.  doi: 10.3969/j.issn.2095-378X.2018.02.012 Abstract ( 160 )   PDF (788KB) ( 421 )   Save Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers.The underlying mechanism of PDAC is not completely revealed yet.Notably, expressions of some long non-coding RNAs (lncRNAs) undergo significant changes in the initiation and progression of cancers.Recent research has demonstrated that lncRNAs have multiple biological functions in cell growth, proliferation, and differentiation.Furthermore, lncRNAs have potential values in the diagnosis, treatment, and prognostic prediction of PDAC.In this review, the molecular mechanism of lncRNAs in PDAC and the potential clinical value were elaborated. References | Related Articles | Metrics

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Research progress on siRNA interference techniquein drug-resistant ovarian cancer LI Xia, TONG Xiaowen 2018, 7 (2):  127-131.  doi: 10.3969/j.issn.2095-378X.2018.02.013 Abstract ( 201 )   PDF (779KB) ( 337 )   Save Ovarian cancer has the highest mortality rate among female reproductive cancer.Because it has no special clinical manifestation in early stage, and the majority of patients are diagnosed in advanced stage.This is a disease with a propensity to recur or deteriorate despite dramatic responses to the treatment of a combination of cytoreductive surgery and platinum-based chemotherapy.RNA interference is a sequence-specific posttranscriptional gene silencing triggered by double-stranded RNA, in which small interfering RNA plays a core role.This paper reviewed the research progress on small interfering RNA technical principle, delivery, and its application in drug-resistant ovarian cancer in recent five years. References | Related Articles | Metrics

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Application progress on horizontal belt plate in the treatment of tibial plateau fracture YAO Xizhou, HU Sunjun, MA Zhuo, ZHANG Shimin 2018, 7 (2):  132-135.  doi: 10.3969/j.issn.2095-378X.2018.02.014 Abstract ( 198 )   PDF (766KB) ( 531 )   Save In the treatment of comminuted fracture of lateral condyle of tibial plateau (involving the entire lateral, posterolateral, and anterolateral), traditional anatomical plate can only be placed on the lateral side of lateral condyle; the proximal arm length is limited for up to four horizontal screws; due to the lack of coverage, part of the fractures cannot be effectively fixed.The fixation with horizontal belt plates is bending straight thin plates and then placing horizontally (such as 3.5 mm 1/3 tube plate, reconstruction plate, and 2.7 mm plate), or modifying thin T-shaped plates by cutting off the side of transverse arm bending trailing arm, and placing horizontally.Such practice increases the coverage in horizontal direction of cracked articular surface.It is an important progress of lateral gather fixation in the treatment of tibial plateau fractures in recent years that it supports and fixes bone blocks in a horizontal manner.This article gave a summary on the topic. References | Related Articles | Metrics

Medical instrument column

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Management of un-priced medical consumables for operation rooms LIN Jiawei, NIU Chunbo, LIU Yinyin, GONG Chungui 2018, 7 (2):  136-142.  doi: 10.3969/j.issn.2095-378X.2018.02.015 Abstract ( 180 )   PDF (1472KB) ( 1117 )   Save Objective To explore the cost control of un-priced medical consumables for operation rooms, improve the efficiency of hospital operation, and provide ideas for relevant management.Methods The quantity and structure of un-priced medical consumables for operation rooms of 2012-2016 were analyzed, and clinical practices were also considered.Results The surgical energy related items accounted for the largest part in the un-priced medical consumables for operation rooms, and the consumption of the anti-corrosive and cleaning items increased by 87.73% within the 5 years.Conclusion The un-priced medical consumables are basically low-cost items, which are often overlooked; however, their various types and huge quantity put big cost pressures on the hospital.Therefore, measures should be taken to enhance the awareness of medical staff regarding cost control, eliminate waste, and effectively control the excessive growth of such items. References | Related Articles | Metrics

Nursing

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Nursing intervention using auricular thumbtack needle buried for perioperative anxiety of patients undergoing breast cancer surgery LI Yanling, LIU Peirong, ZHUANG Juhua, LU Weihua, PENG Sheng 2018, 7 (2):  143-145.  doi: 10.3969/j.issn.2095-378X.2018.02.016 Abstract ( 192 )   PDF (758KB) ( 466 )   Save Objective To observe the effect of auricular acupuncture with thumbtack needle on perioperative anxiety in breast cancer patients.Methods One hundred patients undergoing breast cancer surgery were randomly divided into two groups: treatment group (group T) and control group (group C), 50 patients in each group.The two groups of patients were given the same anesthesia and surgery.One day before surgery, the patients in the group T were treated with auricular acupuncture at Shenmen acupoint, Endocrine acupoint, and Epicardy acupoint with thumbtack needle, while the patients in the group C were treated with fake patch with no needles in the same position.Anxiety scores of the two groups were compared.Results Compared with the group C, the anxiety scores of the group T were reduced at the time entering operation room and 3 days after operation (P<0.05).Conclusion The nursing intervention of auricular acupuncture at Shenmen acupoint,Endocrine acupoint, and Epicardy acupoint with thumbtack needles can relieve perioperative anxiety in breast cancer patients. References | Related Articles | Metrics

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Tolerance analysis and nursing care of nasointestinal tube application after radical resection of esophageal carcinoma BU Su, CHEN Xiaofen, CHEN Fang, WU Shuhui, SONG Cui, XING Limin 2018, 7 (2):  146-149.  doi: 10.3969/j.issn.2095-378X.2018.02.017 Abstract ( 222 )   PDF (817KB) ( 556 )   Save Objective To study the uncomfortable symptoms of the patients who used nasointestinal tubes after radical resection of esophageal carcinoma, analyze causes, and offer corresponding nursing intervention measures.Methods Sixty-five cases who used nasointestinal tubes after radical resection of esophageal carcinoma were selected from The First People’s Hospital, Hubei Institute of Medicine from June 2016 to September 2017.They completed questionnaires about the tolerance to nasointestinal tubes.Uncomfortable symptoms were collected and analyzed, and corresponding nursing interventions were put forward.Results All the sixty-five patients used nasointestinal tubes during operations.Two cases pulled out the tubes by themselves because of discomfort; 2 cases had unplanned extubation because of other reasons (one for blocking in the tube, the other for frequent vomiting); 61 cases removed the tubes after finishing treatment.The incidence rates of different uncomfortable symptoms varied.Conclusion There are many different comfortable symptoms during the use of nasointestinal tubes.Offering nursing care against the causes can obviously improve the tolerance with tubes and help recovery. References | Related Articles | Metrics

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Nursing care for patients with uterine prolapse during laparoscopic uterine suspension and anterior and posterior colporrhaphy CHEN Xiujin 2018, 7 (2):  150-152.  doi: 10.3969/j.issn.2095-378X.2018.02.018 Abstract ( 183 )   PDF (756KB) ( 735 )   Save Objective To summarize the key points of nursing care for patients with uterine prolapse during laparoscopic uterine suspension and anterior and posterior colporrhaphy.Methods A total of 108 patients with uterine prolapse treated from June 2015 to January 2016 in Liyang People’s Hospital were randomly divided into the conventional nursing group and early nursing intervention group, with 54 cases in each group.Both groups received laparoscopic uterine suspension and anterior and posterior colporrhaphy.Self-Rating Anxiety Scale (SAS) score, clinical satisfaction, and nursing quality of the two groups were evaluated.Results The clinical satisfaction level of the early nursing intervention group was higher than that of the conventional nursing group (P＜0.05).Before the intervention, the SAS scores between the two groups were not statistically different (P＞0.05), but after intervention, the SAS score of the early nursing intervention group was higher than that of the conventional nursing group (P＜0.05).The scores of nursing quality in terms of preoperative preparation, mental nursing, discharge instruction, and clinical observation in the conventional nursing group was lower than the scores in the early nursing intervention group (P＜0.05).Conclusion During laparoscopic uterine suspension and anterior and posterior colporrhaphy, early nursing intervention can effectively relieve patient’s anxiety, improve nursing quality, and increase clinical satisfaction. References | Related Articles | Metrics